Anaerobic biotransformation of two novel brominated flame retardants: Kinetics, isotope fractionation and reaction mechanisms

doi:10.1016/j.watres.2023.120360

	Huang, Chenchen 1,2,3,5; Zeng, Yanhong 2,3,4; Hu, Keqi 2,3,4; Jiang, Yiye 2,3,4; Zhang, Yanting 2,3,4; Lu, Qihong 6; Liu, Yin-E 1,2,3; Gao, Shutao2,3,4 ; Wang, Shanquan 6; Luo, Xiaojun2,3,4 ; Mai, Bixian2,3,4
	Anaerobic biotransformation of two novel brominated flame retardants: Kinetics, isotope fractionation and reaction mechanisms
Source Publication	WATER RESEARCH
ISSN	0043-1354
	2023-09-01
Volume	243 Pages:8
DOI	10.1016/j.watres.2023.120360
Language	英语
WOS Research Area	Engineering ; Environmental Sciences & Ecology ; Water Resources
Abstract	1,2,5,6-tetrabromocyclooctane (TBCO) and 2,3-dibromopropyl-2,4,6-tribromophenyl ether (DPTE), as safer al-ternatives to traditional brominated flame retardants, have been extensively detected in various environmental media and pose emerging risks. However, much less is known about their fate in the environment. Anaerobic microbial transformation is a key pathway for the natural attenuation of contaminants. This study investigated, for the first time, the microbial transformation behaviors of fi-TBCO and DPTE by Dehalococcoides mccartyi strain CG1. The results indicated that both fi-TBCO and DPTE could be easily transformed by D. mccartyi CG1 with kobs values of 0.0218 & PLUSMN; 0.0015 h-1 and 0.0089 & PLUSMN; 0.0003 h-1, respectively. In particular, fi-TBCO seemed to undergo dibromo-elimination and then epoxidation to form 4,5-dibromo-9-oxabicyclo[6.1.0]nonane, while DPTE expe-rienced debromination at the benzene ring (ortho-bromine being removed prior to para-bromine) rather than at the carbon chain. Additionally, pronounced carbon and bromine isotope fractionations were observed during biotransformation of fi-TBCO and DPTE, suggesting that C-Br bond breaking is the rate-limiting step of their biotransformation. Finally, coupled with identified products and isotope fractionation patterns, fi-elimination (E2) and Sn2-nucleophilic substitution were considered the most likely microbial transformation mechanisms for fi-TBCO and DPTE, respectively. This work provides important information for assessing the potential of natural attenuation and environmental risks of fi-TBCO and DPTE.
Keyword	Compound-specific isotope analysis Anaerobic microbial transformation Novel brominated flame retardants fi 6-tetrabromocyclooctane 3-dibromopropyl-2 6-tribromophenyl ether
WOS ID	WOS:001051353900001
Indexed By	SCI
Citation statistics	Cited Times:1[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.gig.ac.cn/handle/344008/74693
Collection	有机地球化学国家重点实验室
Corresponding Author	Zeng, Yanhong
Affiliation	1.China Univ Min & Technol, Sch Environm Sci & Spatial Informat, Xuzhou 221116, Jiangsu, Peoples R China 2.Chinese Acad Sci, State Key Lab Organ Geochem, Guangzhou 510640, Peoples R China 3.Chinese Acad Sci, Guangzhou Inst Geochem, Guangdong Key Lab Environm Protect & Resources Uti, Guangzhou 510640, Peoples R China 4.Chinese Acad Sci, Guangzhou Inst Geochem, Guangdong Hong Kong MaCao Joint Lab Environm Pollu, Hong Kong 510640, Guangdong, Peoples R China 5.Key Lab Pollut Exposure & Hlth Intervent Zhejiang, Hangzhou 310015, Peoples R China 6.Sun Yat Sen Univ, Sch Environm Sci & Engn, Guangzhou, Peoples R China
Recommended Citation GB/T 7714	Huang, Chenchen,Zeng, Yanhong,Hu, Keqi,et al. Anaerobic biotransformation of two novel brominated flame retardants: Kinetics, isotope fractionation and reaction mechanisms[J]. WATER RESEARCH,2023,243:8.
APA	Huang, Chenchen.,Zeng, Yanhong.,Hu, Keqi.,Jiang, Yiye.,Zhang, Yanting.,...&Mai, Bixian.(2023).Anaerobic biotransformation of two novel brominated flame retardants: Kinetics, isotope fractionation and reaction mechanisms.WATER RESEARCH,243,8.
MLA	Huang, Chenchen,et al."Anaerobic biotransformation of two novel brominated flame retardants: Kinetics, isotope fractionation and reaction mechanisms".WATER RESEARCH 243(2023):8.

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